abstract：PURPOSE:Assessment of anterior segment-optical coherence tomography angiography (AS-OCTA) to determine severity of corneal neovascularization (CoNV). DESIGN:Retrospective, cross-sectional, single-center study. METHODS:Patients of various CoNV etiologies were selected and classified into mild, moderate, and severe. Th...

journal_title：American journal of ophthalmology

authors： Binotti WW,Koseoglu ND,Nosé RM,Kenyon KR,Hamrah P

更新日期：2020-08-18 00:00:00

abstract：PURPOSE:We sought to assess the agreement of ray-traced corneal power values by 3 Scheimpflug tomographers tp construct the corresponding arithmetic adjustment factor in comparison with an automated keratometer (IOLMaster) and a conventional Placido-based topographer (Allegro Topolyzer). DESIGN:Prospective reliability...

journal_title：American journal of ophthalmology

authors： Pan C,Tan W,Savini G,Hua Y,Ye X,Xu W,Yu J,Wang Q,Huang J

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To evaluate clinically the efficacy of 3600 minimally invasive endoscopic surgery in patients with orbital intraconal tumors. DESIGN:Retrospective interventional case series. METHODS:A series of consecutive patients with orbital intraconal tumors were treated by minimally invasive surgery using an endonasal e...

journal_title：American journal of ophthalmology

authors： Caballero-García J,Aparicio-García C,Linares-Benavides YJ,López-Sánchez M,Abreu-Perdomo FA,Huanca-Amaru J

更新日期：2020-07-29 00:00:00

abstract：PURPOSE:Congenital macular lesions attributed to toxoplasmosis may limit potential visual acuity. The appearance and location of these scars may cause physicians to overlook associated amblyopia. This study reviews the visual outcomes and benefits of amblyopia therapy in children with foveal toxoplasmosis scars. DESIG...

journal_title：American journal of ophthalmology

authors： Reynolds MMM,Chisholm SAM,Schroeder R,Lueder GT

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To determine the test-retest reliability and diagnostic accuracy of a binocular optical coherence tomography (OCT) prototype (Envision Diagnostics, El Segundo, California, USA) for pupillometry. DESIGN:Assessment of diagnostic reliability and accuracy. METHODS:Fifty participants with relative afferent pupilla...

journal_title：American journal of ophthalmology

authors： Chopra R,Mulholland PJ,Petzold A,Ogunbowale L,Gazzard G,Bremner FD,Anderson RS,Keane PA

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To characterize features of glaucoma associated with a TANK binding kinase 1 (TBK1) gene duplication, which is among the most common molecularly defined causes of normal tension glaucoma (NTG). DESIGN:Retrospective observational case series. METHODS:We conducted a retrospective case series, by reviewing medic...

journal_title：American journal of ophthalmology

authors： Quist TS,Johnson CA,Robin AL,Fingert JH

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To clarify the changing characteristics of choroidal thickness over time within different age ranges and among different refractive statuses of children aged 6 to 18 years. DESIGN:Prospective cohort study. METHODS:Data of axial length, cycloplegic refraction, and choroidal thickness (using swept-source optica...

journal_title：American journal of ophthalmology

authors： Xiong S,He X,Zhang B,Deng J,Wang J,Lv M,Zhu J,Zou H,Xu X

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To analyze the biological stability of autologous serum eyedrops after lyophilization. DESIGN:Prospective, comparative experimental study. METHODS:This was a comparative study with serum obtained from 12 healthy volunteers. The concentrations of different epitheliotropic factors (eg, transforming growth facto...

journal_title：American journal of ophthalmology

authors： López-García JS,García-Lozano I,Rivas L,Viso-Garrote M,Raposo R,Méndez MT

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To apply in vivo corneal confocal microscopy (IVCM) to study the pathogenesis of keratitis (keratoendotheliitis) fugax hereditaria, an autosomal dominant cryopyrin-associated periodic keratitis, associated with the c.61G>C pathogenic variant in the NLRP3 gene, in its acute and chronic phase, and to report histo...

journal_title：American journal of ophthalmology

authors： Turunen JA,Immonen AT,Järvinen RS,Kawan S,Repo P,Korsbäck A,Ala-Fossi O,Jaakkola AM,Majander A,Vesaluoma M,Kivelä TT

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:The purpose of this study was to compare the perioperative parameters of quadrant, sextant, and grid lens fragmentation patterns in femtosecond laser-assisted cataract surgery (FLACS). DESIGN:Prospective randomized clinical trial. METHODS:Setting: Eye Center of the Second Affiliated Hospital, School of Medici...

journal_title：American journal of ophthalmology

authors： Lyu D,Shen Z,Zhang L,Qin Z,Ni S,Wang W,Zhu Y,Yao K

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:To identify nationwide trends and factors associated with advanced imaging (computed tomography [CT] and magnetic resonance imaging [MRI]) use for eye-related emergency department (ED) visits. DESIGN:Retrospective, trend study. METHODS:Setting: National Hospital Ambulatory Medical Care Survey 2007-2015. PATI...

journal_title：American journal of ophthalmology

authors： Zafar S,Sebestyen K,Qureshi Z,Schein O,Johnson P,Srikumaran D,Woreta FA

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:This study analyzed and quantified the sources of electronic health record (EHR) text documentation in ophthalmology progress notes. DESIGN:EHR documentation review and analysis. METHODS:Setting: a single academic ophthalmology department. STUDY POPULATION:a cohort study conducted between November 1, 2016, a...

journal_title：American journal of ophthalmology

authors： Henriksen BS,Goldstein IH,Rule A,Huang AE,Dusek H,Igelman A,Chiang MF,Hribar MR

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Periventricular leukomalacia (PVL) is a structural loss of white matter pathways that carry visual information from the lateral geniculate bodies to the visual cortex. It is observed radiologically in patients with a history of prematurity and is associated with visual field (VF) defects and optic disc cupping....

journal_title：American journal of ophthalmology

authors： Groth SL,Donahue SP,Reddy A,Sarma A,Wushensky C

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To assess the effects of sustained gazing on visual function of dry eye patients. DESIGN:Prospective, comparative before-and-after study. METHODS:A total of 176 patients with dry eye and 33 control subjects ≥50 years old were included. Dry eye symptomatology along and clinical parameters were assessed. Out-lo...

journal_title：American journal of ophthalmology

authors： Akpek EK,Karakus S,Ramulu PY,Mathews PM

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To describe the natural history of Leber congenital amaurosis (LCA) associated with GUCY2D variants (GUCY2D-LCA) in a cohort of children and adults, in preparation for trials of novel therapies. DESIGN:Retrospective case series. METHODS:Participants: Patients with GUCY2D-LCA at a single referral center. PROC...

journal_title：American journal of ophthalmology

authors： Bouzia Z,Georgiou M,Hull S,Robson AG,Fujinami K,Rotsos T,Pontikos N,Arno G,Webster AR,Hardcastle AJ,Fiorentino A,Michaelides M

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:To correlate fractal dimension (FD) of the retinal vasculature with the extent of retinal nonperfusion area in diabetic retinopathy (DR) on ultrawide-field fluorescein angiography (FA). DESIGN:Cross-sectional study. METHODS:Baseline Optos 200Tx ultrawide-field FA images of 80 eyes with DR from the DAVE (NCT01...

journal_title：American journal of ophthalmology

authors： Fan W,Nittala MG,Fleming A,Robertson G,Uji A,Wykoff CC,Brown DM,van Hemert J,Ip M,Wang K,Falavarjani KG,Singer M,Sagong M,Sadda SR

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To assess the safety of VR 3D headset (virtual reality 3-dimensional binocular-stereoscopic near-eye display) use in young children. Product safety warnings that accompany VR headsets ban their use in children under age 13 years. DESIGN:Prospective, interventional, before-and-after study. METHODS:Recordings w...

journal_title：American journal of ophthalmology

authors： Tychsen L,Foeller P

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:Wavelength dependence of diffractive intraocular lenses (IOLs) was recognized in vitro but not yet assessed in vivo. By examining pseudophakic patients who had extended-depth-of-focus diffractive implants, this spectral effect on their vision was measured clinically and the lens was tested in vitro. DESIGN:Cro...

journal_title：American journal of ophthalmology

authors： Łabuz G,Auffarth GU,Özen A,van den Berg TJTP,Yildirim TM,Son HS,Khoramnia R

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To evaluate outcomes of patients treated with intensive intravitreal therapy and to describe the evolution of quantitative real-time polymerase chain reaction (qPCR) in patients treated for acute retinal necrosis (ARN) syndrome. DESIGN:Retrospective observational case series. METHODS:This study included 25 ey...

journal_title：American journal of ophthalmology

authors： Hafidi M,Janin-Manificat H,Denis P,Charleux B,Rabilloud M,Boibieux A,Burillon C,Kodjikian L,Frobert E

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To investigate the characteristics, mergers, and risk factors of different types of myopic maculopathy (MM) in a highly myopic population. DESIGN:Population-based, cross-sectional study. METHODS:A total of 1086 eyes (762 patients) were enrolled. Each participant underwent detailed ocular examinations. Combini...

journal_title：American journal of ophthalmology

authors： Chen Q,He J,Hu G,Xu X,Lv H,Yin Y,Zou H,Zhu J,Fan Y,Xu X

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To evaluate the incidence of adverse events (AEs) in patients who underwent refractive lens exchange. DESIGN:Retrospective case series. METHODS:Setting: Private refractive surgery clinics. Patients/Study Population: Patients who underwent refractive lens exchange between July 1, 2014, and June 30, 2016. Inter...

journal_title：American journal of ophthalmology

authors： Schallhorn JM,Schallhorn SC,Teenan D,Hannan SJ,Pelouskova M,Venter JA

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To conduct a qualitative description of corneal and glaucoma outcomes in Peters anomaly. DESIGN:Retrospective case series. METHODS:Children with Peters anomaly who presented between 1982-2017 were included. Visual acuity, intraocular pressure (IOP), survival of corneal grafts, and success of glaucoma surgery ...

journal_title：American journal of ophthalmology

authors： Dolezal KA,Besirli CG,Mian SI,Sugar A,Moroi SE,Bohnsack BL

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:To determine the trends and disparities in inpatient costs for eye trauma in the United States from 2001 through 2014. DESIGN:Retrospective population-based cross-sectional study. METHODS:National Inpatient Sample, a representative sample of U.S. hospital discharges, was used to determine costs of eye trauma ...

journal_title：American journal of ophthalmology

authors： Iftikhar M,Latif A,Usmani B,Canner JK,Shah SMA

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:To compare the long-term efficacy and safety of 2 operation methods for late in-the-bag intraocular lens (IOL) dislocation. DESIGN:Prospective, randomized, parallel group surgical clinical trial. METHODS:During a 3-year period, 104 patients (104 eyes) were assigned one group for IOL repositioning by scleral s...

journal_title：American journal of ophthalmology

authors： Dalby M,Kristianslund O,Drolsum L

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:This study sought to investigate retinal function in patients with noninfectious uveitis by using full-field electroretinography (ERG) and correlate the ERG to disease duration and severity of inflammation. DESIGN:Prospective cohort study. METHODS:Patients (n = 200) with noninfectious uveitis and a disease du...

journal_title：American journal of ophthalmology

authors： Brouwer AH,de Wit GC,Ten Dam NH,Wijnhoven R,van Genderen MM,de Boer JH

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:To describe the genetic and phenotypic characteristics of a cohort of patients with PROM1 variants. DESIGN:Case-case study. METHODS:We screened a cohort of 2216 families with inherited retinal dystrophies using classical molecular techniques and next-generation sequencing approaches. The clinical histories of...

journal_title：American journal of ophthalmology

authors： Del Pozo-Valero M,Martin-Merida I,Jimenez-Rolando B,Arteche A,Avila-Fernandez A,Blanco-Kelly F,Riveiro-Alvarez R,Van Cauwenbergh C,De Baere E,Rivolta C,Garcia-Sandoval B,Corton M,Ayuso C

更新日期：2019-11-01 00:00:00

abstract：PURPOSE:To investigate the prevalence and associations of visual impairment and spectacle use in university students in central China. DESIGN:Cross-sectional study. METHODS:This study included students aged 16-26 years in China. Study subjects from 2 universities underwent distance visual acuity (VA) assessment in bo...

journal_title：American journal of ophthalmology

authors： Wei S,Sun Y,Li SM,Hu J,Cao K,Du J,An W,Liang X,Guo J,Li H,Wang N

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:To evaluate multifocal electroretinography (mfERG) as a screening test for detecting hydroxychloroquine and chloroquine toxicity. DESIGN:Diagnostic accuracy study. METHODS:Patients referred to the University of Ottawa for hydroxychloroquine or chloroquine retinopathy screening during 2011-2014 underwent 10-2 ...

journal_title：American journal of ophthalmology

authors： Tsang AC,Ahmadi S,Hamilton J,Gao J,Virgili G,Coupland SG,Gottlieb CC

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:To compare choroidal vascularity index (CVI) in patients with arteritic anterior ischemic optic neuropathy (A-AION), nonarteritic anterior ischemic optic neuropathy (NA-AION), and control subjects. DESIGN:Retrospective cross-sectional study. METHODS:This study was conducted at the Ophthalmology Unit of the S....

journal_title：American journal of ophthalmology

authors： Pellegrini M,Giannaccare G,Bernabei F,Moscardelli F,Schiavi C,Campos EC

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To compare the effect of age, sex and generation on physician practice patterns in Ontario, Canada. DESIGN:Retrospective cohort study. METHODS:Physician and patient data from 1992-2013 were used to calculate the yearly number of physicians, distinct patients seen, patient visits, government payments, physicia...

journal_title：American journal of ophthalmology

authors： Buys YM,Canizares M,Felfeli T,Jin Y

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To compare the intraocular pressure (IOP)-lowering efficacy and safety of netarsudil once daily (QD) and timolol twice daily (BID). DESIGN:Double-masked, randomized, phase 3, noninferiority study. METHODS:Patients with open-angle glaucoma or ocular hypertension (unmedicated baseline IOP >20 to <30 mm Hg at 8:...

journal_title：American journal of ophthalmology

authors： Khouri AS,Serle JB,Bacharach J,Usner DW,Lewis RA,Braswell P,Kopczynski CC,Heah T,Rocket-4 Study Group.

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To describe the motivations, expectations, and other factors men with X-linked retinoschisis (XLRS) consider when making decisions to participate in an early phase ocular gene therapy clinical trial. DESIGN:Qualitative interview study. METHODS:Men with XLRS who were considering participation in a phase I/IIa ...

journal_title：American journal of ophthalmology

authors： Turriff A,Blain D,Similuk M,Biesecker B,Wiley H,Cukras C,Sieving PA

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:Anterior segment optical coherence tomography (AS-OCT) provides an objective imaging modality for visually identifying anterior segment structures. An automated detection system could assist ophthalmologists in interpreting AS-OCT images for the presence of angle closure. DESIGN:Development of an artificial in...

journal_title：American journal of ophthalmology

authors： Fu H,Baskaran M,Xu Y,Lin S,Wong DWK,Liu J,Tun TA,Mahesh M,Perera SA,Aung T

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:Immune checkpoint inhibitors (ICI) targeting the programmed cell death protein 1 (PD-1), or its ligand PD-L1, are the mainstay of metastatic cancer treatment. Patients receiving these treatments may develop immune-related adverse events (irAEs). This study aimed to estimate the prevalence and describe the clini...

journal_title：American journal of ophthalmology

authors： Bitton K,Michot JM,Barreau E,Lambotte O,Haigh O,Marabelle A,Voisin AL,Mateus C,Rémond AL,Couret C,Champiat S,Labetoulle M,Rousseau A

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To provide evidence that corticosteroid-induced ocular hypertension has a genetic component. DESIGN:Evidence-based perspective. METHODS:We conducted a comprehensive literature search for studies exploring genetic influences on intraocular pressure responses to corticosteroid treatment. RESULTS:Studies demons...

journal_title：American journal of ophthalmology

authors： Chan W,Wiggs JL,Sobrin L

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:To train a deep learning (DL) algorithm that quantifies glaucomatous neuroretinal damage on fundus photographs using the minimum rim width relative to Bruch membrane opening (BMO-MRW) from spectral-domain optical coherence tomography (SDOCT). DESIGN:Cross-sectional study. METHODS:A total of 9282 pairs of opti...

journal_title：American journal of ophthalmology

authors： Thompson AC,Jammal AA,Medeiros FA

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To examine clinical outcomes in deep anterior lamellar keratoplasty (DALK) for keratoconus using contemporary techniques in a multisurgeon public healthcare setting. DESIGN:Consecutive, retrospective case series. METHODS:Setting: Moorfields Eye Hospital, London, United Kingdom. STUDY POPULATION:Consecutive c...

journal_title：American journal of ophthalmology

authors： Gadhvi KA,Romano V,Fernández-Vega Cueto L,Aiello F,Day AC,Allan BD

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To develop patient-derived Pediatric Eye Questionnaires (PedEyeQ) to separately assess eye-related quality of life (ER-QOL) and functional vision in children with eye conditions. DESIGN:Questionnaire development study. METHODS:A total of 444 children (0 to <18 years old), across 10 diagnostic categories, were...

journal_title：American journal of ophthalmology

authors： Hatt SR,Leske DA,Castañeda YS,Wernimont SM,Liebermann L,Cheng-Patel CS,Birch EE,Holmes JM

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:The aim of this study is to investigate temporal trends in multifocal ERG (mfERG) parameters and analyze their relationships with anatomic and functional markers in patients with birdshot chorioretinopathy (BSCR). DESIGN:Prospective observational case series. METHODS:Sixteen BSCR patients were include and und...

journal_title：American journal of ophthalmology

authors： Mailhac A,Labarere J,Aptel F,Berthemy S,Bouillet L,Chiquet C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:To characterize differences in resource utilization and cost of managing enrollees with exfoliation glaucoma (XFG) compared to primary open-angle glaucoma (POAG). DESIGN:Retrospective utilization and cost comparison using Medicare claims data. METHODS:We identified Medicare beneficiaries with XFG or POAG and ...

journal_title：American journal of ophthalmology

authors： Rathi S,Andrews C,Greenfield DS,Stein JD

更新日期：2019-04-01 00:00:00